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Binding sites for blood coagulation factor Xa and protein S involving residues 493-506 in factor Va.

Inactivation due to cleavage of Factor Va (FVa) at Arg 506 by activated protein C (APC) helps to downregulate blood coagulation. To identify potential functional roles of amino acids near Arg 506, synthetic overlapping pentadecapeptides comprising FVa heavy chain residues 481-525 were tested for the...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Heeb, M. J., Kojima, Y., Hackeng, T. M., Griffin, J. H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 1996
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143529/
https://ncbi.nlm.nih.gov/pubmed/8880912
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