Protein structural plasticity exemplified by insertion and deletion mutants in T4 lysozyme.

To further investigate the ways in which proteins respond to changes in the length of the polypeptide chain, a series of 32 insertions and five deletions were made within nine different alpha-helices of T4 lysozyme. In most cases, the inserted amino acid was a single alanine, although in some instan...

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Main Authors: Vetter, I. R., Baase, W. A., Heinz, D. W., Xiong, J. P., Snow, S., Matthews, B. W.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 1996
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143312/
https://ncbi.nlm.nih.gov/pubmed/8976549
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