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Drosophila engrailed-1,10-phenanthroline chimeras as probes of homeodomain-DNA complexes.

We have converted the Drosophila engrailed homeodomain into a sequence-specific nuclease by linking the protein to the chemical nuclease 1,10-phenanthroline-copper (OP-Cu). Unique cysteines were introduced at six positions into the homeodomain by site-directed mutagenesis for the covalent attachment...

詳細記述

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書誌詳細
主要な著者: Pan, C. Q., Landgraf, R., Sigman, D. S.
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 1995
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143021/
https://ncbi.nlm.nih.gov/pubmed/8563624
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