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The influence of reducing agent and 1,10-phenanthroline concentration on DNA cleavage by phenanthroline + copper.

Copper in the presence of excess 1,10-phenanthroline, a reducing agent, and molecular oxygen causes cleavage of DNA with a preference for T-3',5'-A-steps, particularly in TAT triplets. The active molecular species is commonly thought to be the bis-(1,10-phenanthroline)Cu(I) complex, (Phen)...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Veal, J M, Merchant, K, Rill, R L
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1991
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC328338/
https://ncbi.nlm.nih.gov/pubmed/2062655
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