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A 1-deoxy-d-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-d-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis

Several eubacteria including Esherichia coli use an alternative nonmevalonate pathway for the biosynthesis of isopentenyl diphosphate instead of the ubiquitous mevalonate pathway. In the alternative pathway, 2-C-methyl-d-erythritol or its 4-phosphate, which is proposed to be formed from 1-deoxy-d-xy...

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Bibliographic Details
Main Authors: Takahashi, Shunji, Kuzuyama, Tomohisa, Watanabe, Hiroyuki, Seto, Haruo
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1998
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC21430/
https://ncbi.nlm.nih.gov/pubmed/9707569
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