Differentiation of peptide molecular recognition by phospholipase C gamma-1 Src homology-2 domain and a mutant Tyr phosphatase PTP1bC215S.

Activated epidermal growth factor receptor (EGFR) undergoes autophosphorylation on several cytoplasmic tyrosine residues, which may then associate with the src homology-2 (SH2) domains of effector proteins such as phospholipase C gamma-1 (PLC gamma-1). Specific phosphotyrosine (pTyr)-modified EGFR f...

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Detalhes bibliográficos
Main Authors: MacLean, D., Sefler, A. M., Zhu, G., Decker, S. J., Saltiel, A. R., Singh, J., McNamara, D., Dobrusin, E. M., Sawyer, T. K.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2142960/
https://ncbi.nlm.nih.gov/pubmed/7773170
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