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Folding of the multidomain human immunodeficiency virus type-I integrase.

Protein folding conditions were established for human immunodeficiency virus integrase (IN) obtained from purified bacterial inclusion bodies. IN was denatured by 6 M guanidine.HCl-5 mM dithiothreitol, purified by gel filtration, and precipitated by ammonium sulfate. The reversible solvation of prec...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Grandgenett, D. P., Goodarzi, G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 1994
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2142885/
https://ncbi.nlm.nih.gov/pubmed/8069220
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