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Unnatural amino acid packing mutants of Escherichia coli thioredoxin produced by combined mutagenesis/chemical modification techniques.

We have produced several mutants of Escherichia coli thioredoxin (Trx) using a combined mutagenesis/chemical modification technique. The protein C32S, C35S, L78C Trx was produced using standard mutagenesis procedures. After unfolding the protein with guanidine hydrochloride (GdmCl), the normally bur...

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Detalhes bibliográficos
Main Authors: Wynn, R., Richards, F. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 1993
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2142390/
https://ncbi.nlm.nih.gov/pubmed/8453377
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