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Modeling the effects of mutations on the denatured states of proteins.

We develop a model for the reversible denaturation of proteins and for the effects of single-site mutations on the denatured states. The model is based on short chains of sequences of H (hydrophobic) and P (other) monomers configured as self-avoiding walks on the two-dimensional square lattice. The...

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Hlavní autoři: Shortle, D., Chan, H. S., Dill, K. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 1992
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2142194/
https://ncbi.nlm.nih.gov/pubmed/1304903
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