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The calmodulin-binding site of the plasma membrane Ca2+ pump interacts with the transduction domain of the enzyme.

Calpain proteolysis of the plasma membrane Ca2+ pump removes a C-terminal 14-kDa portion which includes the calmodulin-binding domain. This produces a fully activated 124-kDa fragment, which can be inhibited by synthetic versions of the calmodulin-binding domain. The inhibition is strongest when Trp...

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Autori principali: Falchetto, R., Vorherr, T., Carafoli, E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 1992
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2142131/
https://ncbi.nlm.nih.gov/pubmed/1339025
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