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The Guanine Nucleotide Exchange Factor Tiam1 Affects Neuronal Morphology; Opposing Roles for the Small GTPases Rac and Rho

The invasion-inducing T-lymphoma invasion and metastasis 1 (Tiam1) protein functions as a guanine nucleotide exchange factor (GEF) for the small GTPase Rac1. Differentiation-dependent expression of Tiam1 in the developing brain suggests a role for this GEF and its effector Rac1 in the control of neu...

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Main Authors: van Leeuwen, Frank N., Kain, Hendrie E.T., van der Kammen, Rob A., Michiels, Frits, Kranenburg, Onno W., Collard, John G.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1997
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2141700/
https://ncbi.nlm.nih.gov/pubmed/9348295
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