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Targeted Deletion of the PEX2 Peroxisome Assembly Gene in Mice Provides a Model for Zellweger Syndrome, a Human Neuronal Migration Disorder

Zellweger syndrome is a peroxisomal biogenesis disorder that results in abnormal neuronal migration in the central nervous system and severe neurologic dysfunction. The pathogenesis of the multiple severe anomalies associated with the disorders of peroxisome biogenesis remains unknown. To study the...

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Détails bibliographiques
Auteurs principaux: Faust, Phyllis L., Hatten, Mary E.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1997
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2140200/
https://ncbi.nlm.nih.gov/pubmed/9382874
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