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Targeted Deletion of the PEX2 Peroxisome Assembly Gene in Mice Provides a Model for Zellweger Syndrome, a Human Neuronal Migration Disorder

Zellweger syndrome is a peroxisomal biogenesis disorder that results in abnormal neuronal migration in the central nervous system and severe neurologic dysfunction. The pathogenesis of the multiple severe anomalies associated with the disorders of peroxisome biogenesis remains unknown. To study the...

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Main Authors: Faust, Phyllis L., Hatten, Mary E.
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 1997
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2140200/
https://ncbi.nlm.nih.gov/pubmed/9382874
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