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SUMO-1 Modification and Its Role in Targeting the Ran GTPase-activating Protein, RanGAP1, to the Nuclear Pore Complex

RanGAP1 is the GTPase-activating protein for Ran, a small ras-like GTPase involved in regulating nucleocytoplasmic transport. In vertebrates, RanGAP1 is present in two forms: one that is cytoplasmic, and another that is concentrated at the cytoplasmic fibers of nuclear pore complexes (NPCs). The NPC...

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Главные авторы: Matunis, Michael J., Wu, Jian, Blobel, Günter
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 1998
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2140169/
https://ncbi.nlm.nih.gov/pubmed/9456312
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