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LFA-1–mediated Adhesion Is Regulated by Cytoskeletal Restraint and by a Ca(2+)-dependent Protease, Calpain

The activity of integrins on leukocytes is kept under tight control to avoid inappropriate adhesion while these cells are circulating in blood or migrating through tissues. Using lymphocyte function-associated antigen-1 (LFA-1) on T cells as a model, we have investigated adhesion to ligand intercell...

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Autores principales: Stewart, Mairi P., McDowall, Alison, Hogg, Nancy
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2140165/
https://ncbi.nlm.nih.gov/pubmed/9456328
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