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Intraperitoneal Injection of an hpRNA-expressing Plasmid Targeting uPAR and uPA Retards Angiogenesis and Inhibits Intracranial Tumor Growth in Nude Mice
PURPOSE: The purpose of this study was to evaluate the therapeutic potential of using plasmid expressed RNAi targeting uPAR and uPA to treat human glioma. EXPERIMENTAL DESIGN: In the present study, we have used plasmid based RNAi to simultaneously downregulate the expression of uPAR and uPA in SNB19...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2139987/ https://ncbi.nlm.nih.gov/pubmed/17634529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-06-3032 |
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