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Segregation of Glucosylceramide and Sphingomyelin Occurs in the Apical to Basolateral Transcytotic Route in HepG2 Cells

HepG2 cells are highly differentiated hepatoma cells that have retained an apical, bile canalicular (BC) plasma membrane polarity. We investigated the dynamics of two BC-associated sphingolipids, glucosylceramide (GlcCer) and sphingomyelin (SM). For this, the cells were labeled with fluorescent acyl...

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Autors principals: van IJzendoorn, Sven C.D., Zegers, Mirjam M.P., Kok, Jan Willem, Hoekstra, Dick
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2139765/
https://ncbi.nlm.nih.gov/pubmed/9128247
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