Human endplate acetylcholinesterase deficiency caused by mutations in the collagen-like tail subunit (ColQ) of the asymmetric enzyme
In skeletal muscle, acetylcholinesterase (AChE) exists in homomeric globular forms of type T catalytic subunits (ACHE(T)) and heteromeric asymmetric forms composed of 1, 2, or 3 tetrameric ACHE(T) attached to a collagenic tail (ColQ). Asymmetric AChE is concentrated at the endplate (EP), where its c...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21394/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9689136/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.16.9654 |
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