Human endplate acetylcholinesterase deficiency caused by mutations in the collagen-like tail subunit (ColQ) of the asymmetric enzyme

In skeletal muscle, acetylcholinesterase (AChE) exists in homomeric globular forms of type T catalytic subunits (ACHE(T)) and heteromeric asymmetric forms composed of 1, 2, or 3 tetrameric ACHE(T) attached to a collagenic tail (ColQ). Asymmetric AChE is concentrated at the endplate (EP), where its c...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Ohno, Kinji, Brengman, Joan, Tsujino, Akira, Engel, Andrew G.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1998
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21394/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9689136/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.16.9654
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!