Presenilin 1 associates with glycogen synthase kinase-3β and its substrate tau

Families bearing mutations in the presenilin 1 (PS1) gene develop Alzheimer’s disease. Previous studies have shown that the Alzheimer-associated mutations in PS1 increase production of amyloid β protein (Aβ(1–42)). We now show that PS1 also regulates phosphorylation of the microtubule-associated pro...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Takashima, Akihiko, Murayama, Miyuki, Murayama, Ohoshi, Kohno, Toshiyuki, Honda, Toshiyuki, Yasutake, Kaori, Nihonmatsu, Naomi, Mercken, Marc, Yamaguchi, Haruyasu, Sugihara, Shiro, Wolozin, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC21391/
https://ncbi.nlm.nih.gov/pubmed/9689133
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados