The hereditary renal cell carcinoma 3;8 translocation fuses FHIT to a patched-related gene, TRC8

The 3;8 chromosomal translocation, t(3;8)(p14.2;q24.1), was described in a family with classical features of hereditary renal cell carcinoma. Previous studies demonstrated that the 3p14.2 breakpoint interrupts the fragile histidine triad gene (FHIT) in its 5′ noncoding region. However, evidence that...

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Autori principali: Gemmill, Robert M., West, James D., Boldog, Ferenc, Tanaka, Naotake, Robinson, Linda J., Smith, David I., Li, Frederick, Drabkin, Harry A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1998
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC21380/
https://ncbi.nlm.nih.gov/pubmed/9689122
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