The tumor suppressor gene TRC8/RNF139 is disrupted by a constitutional balanced translocation t(8;22)(q24.13;q11.21) in a young girl with dysgerminoma

BACKGROUND: RNF139/TRC8 is a potential tumor suppressor gene with similarity to PTCH, a tumor suppressor implicated in basal cell carcinomas and glioblastomas. TRC8 has the potential to act in a novel regulatory relationship linking the cholesterol/lipid biosynthetic pathway with cellular growth con...

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Bibliografiset tiedot
Päätekijät: Gimelli, Stefania, Beri, Silvana, Drabkin, Harry A, Gambini, Claudio, Gregorio, Andrea, Fiorio, Patrizia, Zuffardi, Orsetta, Gemmill, Robert M, Giorda, Roberto, Gimelli, Giorgio
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2009
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727492/
https://ncbi.nlm.nih.gov/pubmed/19642973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-52
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