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The fibrin-derived γ(377-395) peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease
Perivascular microglia activation is a hallmark of inflammatory demyelination in multiple sclerosis (MS), but the mechanisms underlying microglia activation and specific strategies to attenuate their activation remain elusive. Here, we identify fibrinogen as a novel regulator of microglia activation...
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| Главные авторы: | , , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2137908/ https://ncbi.nlm.nih.gov/pubmed/17339406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061931 |
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