Peripheral regions of natural hammerhead ribozymes greatly increase their self-cleavage activity
Natural hammerhead ribozymes are mostly found in some viroid and viroid-like RNAs and catalyze their cis cleavage during replication. Hammerheads have been manipulated to act in trans and assumed to have a similar catalytic behavior in this artificial context. However, we show here that two natural...
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| Pubblicato in: | EMBO J |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC213784/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14532128/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg530 |
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