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Peripheral regions of natural hammerhead ribozymes greatly increase their self-cleavage activity
Natural hammerhead ribozymes are mostly found in some viroid and viroid-like RNAs and catalyze their cis cleavage during replication. Hammerheads have been manipulated to act in trans and assumed to have a similar catalytic behavior in this artificial context. However, we show here that two natural...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2003
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC213784/ https://ncbi.nlm.nih.gov/pubmed/14532128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg530 |
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