SCF(HOS) ubiquitin ligase mediates the ligand-induced down-regulation of the interferon-α receptor

Down-regulation of activated signaling receptors in response to their ligands plays a key role in restricting the extent and duration of the signaling. Mechanisms underlying down-regulation of the type I interferon receptor consisting of IFNAR1 and IFNAR2 subunits remain largely unknown. Here we sho...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Suresh Kumar, K.G., Tang, Weigang, Ravindranath, Abhilash K., Clark, William A., Croze, Ed, Fuchs, Serge Y.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2003
Assuntos:	Articles
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC213778/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14532120/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg524
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