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Determination of lymphoid cell fate is dependent on the expression status of the IL-7 receptor

Signaling through the IL-7 receptor (IL-7R) is necessary for the development of the earliest B- and T-lineage cells. IL-7R is first expressed on common lymphoid progenitor cells and is not detected on primitive common myeloid progenitors. In this study, we show that enforced expression of IL-7R on m...

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Detalhes bibliográficos
Main Authors: Purohit, Sheetal J., Stephan, Robert P., Kim, Hyung-Gyoon, Herrin, Brantley R., Gartland, Larry, Klug, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC213776/
https://ncbi.nlm.nih.gov/pubmed/14532123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg522
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