IL-7/IL-7R gene variants impact circulating IL-7/IL-7R homeostasis and ART-associated immune recovery status

A relationship between polymorphisms in genes encoding interleukin 7 (IL-7) and its cellular receptor (IL-7R) and antiretroviral therapy (ART)-associated immune recovery in HIV subjects has been previously reported. However, details of this relationship remain unclear, and the association of these p...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Ceausu, Andra, Rodríguez-Gallego, Esther, Peraire, Joaquim, López-Dupla, Miguel, Domingo, Pere, Viladés, Consuelo, Vidal-Gonzalez, Judit, Peraire, Maria, Perpiñán, Carles, Pacheco, Yolanda María, Veloso, Sergi, Alba, Verónica, Vargas, Montserrat, Castellano, Alfonso J., Ruiz-Mateos, Ezequiel, Mallolas, Josep, Vidal, Francesc, Rull, Anna
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6823538/
https://ncbi.nlm.nih.gov/pubmed/31673011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52025-8
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