High circulating SDF-1and MCP-1 levels and genetic variations in CXCL12, CCL2 and CCR5: Prognostic signature of immune recovery status in treated HIV-positive patients

BACKGROUND: The underlying mechanisms of incomplete immune reconstitution in treated HIV-positive patients are very complex and may be multifactorial, but perturbation of chemokine secretion could play a key role in CD4(+)T-cell turnover. METHODS: We evaluated the circulating baseline and 48-week fo...

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Dettagli Bibliografici
Pubblicato in:EBioMedicine
Autori principali: Yeregui, Elena, Viladés, Consuelo, Domingo, Pere, Ceausu, Andra, Pacheco, Yolanda María, Veloso, Sergi, Inciarte, Alexy, Vidal-González, Judit, Peraire, Maria, Perpiñán, Carles, Falcó, Vicenç, Masip, Jenifer, Alba, Verónica, Vargas, Montserrat, Martí, Anna, Reverté, Laia, Mallolas, Josep, Vidal, Francesc, Peraire, Joaquim, Rull, Anna
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653063/
https://ncbi.nlm.nih.gov/pubmed/33166788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.103077
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