A mouse model of severe von Willebrand disease: Defects in hemostasis and thrombosis
von Willebrand factor (vWf) deficiency causes severe von Willebrand disease in humans. We generated a mouse model for this disease by using gene targeting. vWf-deficient mice appeared normal at birth; they were viable and fertile. Neither vWf nor vWf propolypeptide (von Willebrand antigen II) were d...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1998
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21371/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9689113/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.16.9524 |
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