A mouse model of severe von Willebrand disease: Defects in hemostasis and thrombosis

von Willebrand factor (vWf) deficiency causes severe von Willebrand disease in humans. We generated a mouse model for this disease by using gene targeting. vWf-deficient mice appeared normal at birth; they were viable and fertile. Neither vWf nor vWf propolypeptide (von Willebrand antigen II) were d...

Full description

Saved in:
Bibliographic Details
Main Authors: Denis, Cécile, Methia, Nassia, Frenette, Paul S., Rayburn, Helen, Ullman-Culleré, Mollie, Hynes, Richard O., Wagner, Denisa D.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1998
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC21371/
https://ncbi.nlm.nih.gov/pubmed/9689113
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items