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Mechanism of Inducible Nitric Oxide Synthase Exclusion from Mycobacterial Phagosomes

Mycobacterium tuberculosis is sensitive to nitric oxide generated by inducible nitric oxide synthase (iNOS). Consequently, to ensure its survival in macrophages, M. tuberculosis inhibits iNOS recruitment to its phagosome by an unknown mechanism. Here we report the mechanism underlying this process,...

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Bibliografiske detaljer
Main Authors: Davis, Alexander S, Vergne, Isabelle, Master, Sharon S, Kyei, George B, Chua, Jennifer, Deretic, Vojo
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2134953/
https://ncbi.nlm.nih.gov/pubmed/18069890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0030186
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