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Mechanism of Inducible Nitric Oxide Synthase Exclusion from Mycobacterial Phagosomes

Mycobacterium tuberculosis is sensitive to nitric oxide generated by inducible nitric oxide synthase (iNOS). Consequently, to ensure its survival in macrophages, M. tuberculosis inhibits iNOS recruitment to its phagosome by an unknown mechanism. Here we report the mechanism underlying this process,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Davis, Alexander S, Vergne, Isabelle, Master, Sharon S, Kyei, George B, Chua, Jennifer, Deretic, Vojo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2134953/
https://ncbi.nlm.nih.gov/pubmed/18069890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0030186
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