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A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex

Ran is a nuclear Ras-like GTPase that is required for the bidirectional transport of proteins and ribnucleoproteins across the nuclear pore complex (NPC). A key regulator of the Ran GTP/GDP cycle is the 70-kD Ran-GTPase-activating protein RanGAP1. Here, we report the identification and localization...

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Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2133973/
https://ncbi.nlm.nih.gov/pubmed/8978815
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