Mutation of the polo-box disrupts localization and mitotic functions of the mammalian polo kinase Plk
Members of the polo subfamily of protein kinases play pivotal roles in cell proliferation. In addition to the kinase domain, polo kinases have a strikingly conserved sequence in the noncatalytic domain, termed the polo-box. The function of the polo-box is currently undefined. The mammalian polo-like...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1998
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21333/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9689075/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.16.9301 |
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