Polo-like Kinase 1 (PLK1) Inhibitors Targeting Anticancer Activity
Polo-like kinase 1 (PLK1) is a serine/threonine kinase that orchestrates multiple critical events during mitosis, including centrosome maturation, spindle assembly, kinetochore–microtubule attachment, and cytokinesis. Dysregulation and overexpression of PLK1 are frequently observed in various cancer...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI AG
2025-11-01
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| coleção: | Kinases and Phosphatases |
| Assuntos: | |
| Acesso em linha: | https://www.mdpi.com/2813-3757/3/4/23 |
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