Domains of Axin Involved in Protein–Protein Interactions, Wnt Pathway Inhibition, and Intracellular Localization

Axin was identified as a regulator of embryonic axis induction in vertebrates that inhibits the Wnt signal transduction pathway. Epistasis experiments in frog embryos indicated that Axin functioned downstream of glycogen synthase kinase 3β (GSK3β) and upstream of β-catenin, and subsequent studies sh...

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Autores principales: Fagotto, François, Jho, Eek-hoon, Zeng, Li, Kurth, Thomas, Joos, Thomas, Kaufmann, Christine, Costantini, Frank
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1999
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Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2133179/
https://ncbi.nlm.nih.gov/pubmed/10330403
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