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Domains of Axin Involved in Protein–Protein Interactions, Wnt Pathway Inhibition, and Intracellular Localization

Axin was identified as a regulator of embryonic axis induction in vertebrates that inhibits the Wnt signal transduction pathway. Epistasis experiments in frog embryos indicated that Axin functioned downstream of glycogen synthase kinase 3β (GSK3β) and upstream of β-catenin, and subsequent studies sh...

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Hlavní autoři: Fagotto, François, Jho, Eek-hoon, Zeng, Li, Kurth, Thomas, Joos, Thomas, Kaufmann, Christine, Costantini, Frank
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2133179/
https://ncbi.nlm.nih.gov/pubmed/10330403
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