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Characterization of HIV-1 Vpr Nuclear Import: Analysis of Signals and Pathways

While the Vpr protein of HIV-1 has been implicated in import of the viral preintegration complex across the nuclear pore complex (NPC) of nondividing cellular hosts, the mechanism by which Vpr enters the nucleus remains unknown. We now demonstrate that Vpr contains two discrete nuclear targeting sig...

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Detalhes bibliográficos
Main Authors: Jenkins, Yonchu, McEntee, Michele, Weis, Karsten, Greene, Warner C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2132945/
https://ncbi.nlm.nih.gov/pubmed/9817747
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