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Similarities and Differences in RANTES- and (AOP)-RANTES–triggered Signals: Implications for Chemotaxis

Chemokines are a family of proinflammatory cytokines that attract and activate specific types of leukocytes. Chemokines mediate their effects via interaction with seven transmembrane G protein–coupled receptors (GPCR). Using CCR5-transfected HEK-293 cells, we show that both the CCR5 ligand, RANTES,...

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Detalhes bibliográficos
Main Authors: Rodríguez-Frade, José M., Vila-Coro, Antonio J., Martín, Ana, Nieto, Marta, Sánchez-Madrid, Francisco, Proudfoot, Amanda E.I., Wells, Timothy N.C., Martínez-A, Carlos, Mellado, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2132943/
https://ncbi.nlm.nih.gov/pubmed/10037796
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