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The chemokine monocyte chemoattractant protein-1 induces functional responses through dimerization of its receptor CCR2

Cytokines interact with hematopoietin superfamily receptors and stimulate receptor dimerization. We demonstrate that chemoattractant cytokines (chemokines) also trigger biological responses through receptor dimerization. Functional responses are induced after pairwise crosslinking of chemokine recep...

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Detalhes bibliográficos
Main Authors: Rodríguez-Frade, José Miguel, Vila-Coro, Antonio J., Martín de Ana, Ana, Albar, Juan Pablo, Martínez-A., Carlos, Mellado, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22345/
https://ncbi.nlm.nih.gov/pubmed/10097088
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