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Disruption of the Talin Gene Compromises Focal Adhesion Assembly in Undifferentiated but Not Differentiated Embryonic Stem Cells

We have used gene disruption to isolate two talin (−/−) ES cell mutants that contain no intact talin. The undifferentiated cells (a) were unable to spread on gelatin or laminin and grew as rounded colonies, although they were able to spread on fibronectin (b) showed reduced adhesion to laminin, but...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Priddle, Helen, Hemmings, Lance, Monkley, Susan, Woods, Alison, Patel, Bipin, Sutton, Deborah, Dunn, Graham A., Zicha, Daniel, Critchley, David R.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The Rockefeller University Press 1998
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2132864/
https://ncbi.nlm.nih.gov/pubmed/9722622
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