Transfer of Free Polymannose-type Oligosaccharides from the Cytosol to Lysosomes in Cultured Human Hepatocellular Carcinoma HEPG2 Cells

Large, free polymannose oligosaccharides generated during glycoprotein biosynthesis rapidly appear in the cytosol of HepG2 cells where they undergo processing by a cytosolic endo H–like enzyme and a mannosidase to yield the linear isomer of Man(5)GlcNAc (Man[α1-2]Man[α1-2]Man[α1-3][Man α1-6]Man[β14]...

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Bibliographic Details
Main Authors: Saint-Pol, Agnès, Bauvy, Chantal, Codogno, Patrice, Moore, Stuart E.H.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1997
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2132453/
https://ncbi.nlm.nih.gov/pubmed/9008702
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