Superoxide generation by endothelial nitric oxide synthase: The influence of cofactors

The mechanism of superoxide generation by endothelial nitric oxide synthase (eNOS) was investigated by the electron spin resonance spin-trapping technique using 5-diethoxyphosphoryl-5-methyl-1-pyrroline N-oxide. In the absence of calcium/calmodulin, eNOS produces low amounts of superoxide. Upon acti...

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Библиографические подробности
Главные авторы: Vásquez-Vivar, Jeannette, Kalyanaraman, B., Martásek, Pavel, Hogg, Neil, Masters, Bettie Sue Siler, Karoui, Hakim, Tordo, Paul, Pritchard, Kirkwood A.
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 1998
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC21319/
https://ncbi.nlm.nih.gov/pubmed/9689061
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