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TRAIL-R deficiency in mice promotes susceptibility to chronic inflammation and tumorigenesis
Preclinical data support the potential of the death-signaling receptors for TRAIL as targets for cancer therapy. However, it is unclear whether these death-signaling receptors suppress the emergence and growth of malignant tumors in vivo. Herein we show that TNF-related apoptosis-inducing ligand rec...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2129232/ https://ncbi.nlm.nih.gov/pubmed/18079962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29900 |
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