Molecular Dynamic Simulations of Cisplatin- and Oxaliplatin-d(GG) Intrastand Cross-Links Reveal Differences in their Conformational Dynamics

Mismatch repair proteins, DNA damage-recognition proteins and translesion DNA polymerases discriminate between Pt-GG adducts containing cis-diammine ligands (formed by cisplatin (CP) and carboplatin) and trans-RR-diaminocyclohexane ligands (formed by oxaliplatin (OX)) and this discrimination is thou...

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Detaylı Bibliyografya
Asıl Yazarlar: Sharma, Shantanu, Gong, Peng, Temple, Brenda, Bhattacharyya, Debadeep, Dokholyan, Nikolay V., Chaney, Stephen G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2129172/
https://ncbi.nlm.nih.gov/pubmed/17900616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.07.079
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