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PTEN modulates GDNF/RET mediated chemotaxis and branching morphogenesis in the developing kidney

The RET receptor tyrosine kinase is activated by GDNF and controls outgrowth and invasion of the ureteric bud epithelia in the developing kidney. In renal epithelial cells and in enteric neuronal precursor cells, activation of RET results in chemotaxis as Ret expressing cells invade the surrounding...

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Bibliografiske detaljer
Main Authors: Kim, Doyeob, Dressler, Gregory R.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2129124/
https://ncbi.nlm.nih.gov/pubmed/17540362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.04.051
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