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PTEN modulates GDNF/RET mediated chemotaxis and branching morphogenesis in the developing kidney
The RET receptor tyrosine kinase is activated by GDNF and controls outgrowth and invasion of the ureteric bud epithelia in the developing kidney. In renal epithelial cells and in enteric neuronal precursor cells, activation of RET results in chemotaxis as Ret expressing cells invade the surrounding...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2129124/ https://ncbi.nlm.nih.gov/pubmed/17540362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.04.051 |
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