Transcription Factor 21 Is Required for Branching Morphogenesis and Regulates the Gdnf-Axis in Kidney Development

BACKGROUND: The mammalian kidney develops through reciprocal inductive signals between the metanephric mesenchyme and ureteric bud. Transcription factor 21 (Tcf21) is highly expressed in the metanephric mesenchyme, including Six2-expressing cap mesenchyme and Foxd1-expressing stromal mesenchyme. Tcf...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Ide, Shintaro, Finer, Gal, Maezawa, Yoshiro, Onay, Tuncer, Souma, Tomokazu, Scott, Rizaldy, Ide, Kana, Akimoto, Yoshihiro, Li, Chengjin, Ye, Minghao, Zhao, Xiangmin, Baba, Yusuke, Minamizuka, Takuya, Jin, Jing, Takemoto, Minoru, Yokote, Koutaro, Quaggin, Susan E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2018
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287866/
https://ncbi.nlm.nih.gov/pubmed/30377232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017121278
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