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Efficacy of On-Demand Asimadoline, a Peripheral Κ-Opioid Agonist, in Females with Irritable Bowel Syndrome
BACKGROUND: In experimental animal models of irritable bowel syndrome (IBS) and human studies, peripheral kappa opioid agonists have been demonstrated to decrease sensation to colonic distention. AIMS: To compare the effects of the kappa opioid agonist, asimadoline, and placebo on episodes of abdomi...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2128734/ https://ncbi.nlm.nih.gov/pubmed/17900994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cgh.2007.07.011 |
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