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A new palladium-mediated approach to 4-N-arylamino-1-butanols from peroxidic tetrahydrofuran and primary aromatic amines
Reaction of primary aromatic amines with peroxidic tetrahydrofuran (THF) in the presence of hydrogen and 10% palladium on carbon catalyst results in THF ring opening to give 4-N-arylamino-1-butanols in good yield. The reaction mechanism is believed to involve a free-radical sequence resulting in an...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2128685/ https://ncbi.nlm.nih.gov/pubmed/18071580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2006.12.136 |
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