Thermodynamic criteria for high hit rate antisense oligonucleotide design
Antisense oligonucleotides are used for therapeutic applications and in functional genomic studies. In practice, however, many of the oligonucleotides complementary to an mRNA have little or no antisense activity. Theoretical strategies to improve the ‘hit rate’ in antisense screens will reduce the...
Na minha lista:
| Publicado no: | Nucleic Acids Res |
|---|---|
| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC212809/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12930948/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg710 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|